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METABOLIC DETOXICATION, PHASE II
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DeCS
Descriptor
English
:
Metabolic Detoxication, Phase II
Descriptor
Spanish
:
Fase II de la Desintoxicación Metabólica
Descriptor
Portuguese
:
Desintoxicação Metabólica Fase II
Tree Number:
G03.495.244.450.750
G03.787.225.450.750
G07.690.725.225.450.750
Definition
English
:
The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include
GLUTATHIONE
conjugation;
ACYLATION
; and
AMINATION
. Phase II
enzymes
include
GLUTATHIONE TRANSFERASE
and
GLUCURONOSYLTRANSFERASE
. In a sense these reactions detoxify phase I reaction products.
See Related
English
:
Antioxidant Response Elements
Protein Processing, Post-Translational
History Note
English
:
2006
Allowable Qualifiers
English
:
EH
ethnology
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
51247
Unique Identifier:
D050217
Occurrence in VHL
:
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DeCS
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